Does DNA methylation mediate the association of age at puberty with forced vital capacity or forced expiratory volume in 1 s?
Background Age of pubertal onset is associated with lung function in adulthood.However, the underlying role of epigenetics as a mediator of this association remains unknown.Methods DNA methylation (DNAm) in peripheral blood was measured at age 18 years in the Isle of Wight birth cohort (IOWBC) along with data on age of pubertal events, forced vital