DOES DNA METHYLATION MEDIATE THE ASSOCIATION OF AGE AT PUBERTY WITH FORCED VITAL CAPACITY OR FORCED EXPIRATORY VOLUME IN 1 S?

Does DNA methylation mediate the association of age at puberty with forced vital capacity or forced expiratory volume in 1 s?

Background Age of pubertal onset is associated with lung function in adulthood.However, the underlying role of epigenetics as a mediator of this association remains unknown.Methods DNA methylation (DNAm) in peripheral blood was measured at age 18 years in the Isle of Wight birth cohort (IOWBC) along with data on age of pubertal events, forced vital

read more

Modulation of protein fermentation does not affect fecal water toxicity: a randomized cross-over study in healthy subjects.

Protein fermentation results in production of metabolites such as ammonia, amines and indolic, phenolic and sulfur-containing compounds.In vitro studies suggest that these metabolites might be toxic.However, human and animal studies do not consistently support these findings.We modified steely dan gaucho t-shirt protein fermentation in healthy subj

read more

From decentralization to commonization of HIV healthcare resources: keys to reduction in health disparity and equitable distribution of health services in Nigeria

Access to quality care is essential for improved health outcomes.Decentralization improves access to healthcare services at lower levels of care, but it salamander chameleon does not dismantle structural, funding and programming restrictions to access, resulting in inequity and inequality in population health.Unlike decentralization, Commonization

read more

Common Risk Factors for Urinary House Soiling (Periuria) in Cats and Its Differentiation: The Sensitivity and Specificity of Common Diagnostic Signs

Urinary house soiling (periuria) in the home is a common but serious behaviour problem in cats.Although many specific risk factors and triggers have been postulated, their importance is largely unknown.This study assessed: (1) the significance of purported risk factors for periuria as well as specifically marking and latrine behaviour in the home;

read more